In an era of rapid advancements in precision medicine and genomics, whole exome sequencing has emerged as a pivotal technological tool driving both research and clinical applications. However, the perfect synergy of high uniformity, high efficiency, and low cost has long been the relentless pursuit of researchers and enterprises. As one of China earliest high-tech companies specializing in probe capture technology, iGeneTech has remained committed to deepening its foundational core technologies. Since launching China first domestic whole exome product in 2017 and collaborating with Fudan University to establish the "Huabiao Database" of Chinese whole exomes, the company has consistently served numerous research and corporate users.
Now, iGeneTech proudly unveils its brand-new upgraded version "AIExome V5," leveraging exceptional performance and technological innovation to break through the limitations of international brands and redefine the industry’s competitive landscape.
Highlight 1: Achieve Better Uniformity — Best-in-Class No Longer Exclusively a Label for Overseas Brands
Leveraging innovative probe design and optimization, AIExome V5 effectively reduces bias in high-GC or low-GC regions, ensuring more uniform coverage across target regions. The uniformity metric (Fold 80) has achieved a remarkable breakthrough, reaching an impressive 1.24. When paired with the latest 2-hour rapid hybridization capture protocol, Fold 80 remains stably controlled at 1.5. These performance metrics far outpace competitor products on the market.
Highlight 2: Efficient Capture Protocol — Redefining the Balance Between Speed and Performance
AIExome V5 employs an upgraded hybridization capture technology, achieving the fastest 2-hour rapid hybridization system while maintaining exceptional performance. This ensures high-quality and efficient enrichment of target region fragments in a short time, significantly enhancing research efficiency. Coupled with industry-leading probe capture capabilities, researchers can enjoy unprecedented flexibility and efficiency, setting a new standard for speed-performance balance in the market.
Highlight 3: Superior Data and Comprehensive Coverage
Through its multi-layer tilling probe design and intelligent probe selection technology, AIExome V5 achieves a perfect balance between coverage and accuracy. Compared to the "best coverage" claimed by most manufacturers in the market, AIExome V5 not only delivers 20%× coverage performance superior to 99% of them in target regions but also achieves higher 20× and 30× coverage ratios at the same data volume. Additionally, it exhibits fewer poorly covered exons in OMIM genes, setting a new benchmark for comprehensive and precise genomic coverage.
Expert Comment:
Dr. Zhou Zaiwei, a renowned genetic analysis interpretation expert, shared his insights: "I tested your new WES, and it’s truly impressive. At the same data volume, it achieves higher 20× and 30× coverage ratios, and there are fewer poorly covered exons in OMIM genes compared to certain competitor products."
The uniformity index has been elevated to the leading level in the industry. The coverage difference in the target regions is significantly reduced, ensuring the stable and reliable data quality of each sample.
Whether for scientific research exploration or clinical diagnosis, the new version of the kit can provide high-efficiency and stable capture performance. It is compatible with multiple sequencing platforms to meet diverse needs.
The experimental process is optimized, the operation is simplified, and human errors are reduced. This ensures that the experimental results are highly repeatable, enabling users to quickly obtain high-quality data.
iGeneTech Ushered in a New Era of Gene Sequencing
iGeneTech fully understands the significance of scientific research needs. The AIExome V5 not only inherits our consistent tradition of high - performance but also innovatively incorporates new functions, offering users a more flexible configuration method and precise technical support. We are committed to continuously providing the market with more cost - effective and high - performance whole exome capture solutions through persistent innovation and the pursuit of excellence.
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