iGeneTech Bioscience Co., Ltd.
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AIExome® Human Exome Panel V3

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Overview
Versions
Advantages
Performance
Ordering Info
Resources

Overview

AIExome® Human Exome Panel V3 is designed based on human reference genome GRCh38. It covers about 34.4 Mb CDS region, and the probe coverage size is only 44.6 Mb, ensuring maximum coverage of the protein-coding region. AIExome® V3 has also been optimized for probe coverage of reference genome patches, high repeat regions and high GC content regions. AIExome® V3 series has 3 different versions and is open to semi-customization, where customers can add or enhance probes for regions of interests based on standard AIExome® V3.




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Product Parameters

Panel NumberT600V1
Technical PlatformTargetSeq® Hybridization Capture Sequencing
Coverage Size34.4 Mb
Reference DatabaseRefSeq、MANE、CCDS etc.
Reference GenomeGRCh38 (hg38)
CoverageCDS
Storage<-70℃
Sequence PlatformIllumina / MGI
Recommend Sequencing Read LengthPE150
Recommend Sequencing Data Size and Depth8Gb / 100X



Versions

The AIExome® Human Exome Panel V3 product is available in 3 versions:


CDS Region
Internal Reference QC SNPsClinVarMitochondriaSNP BackboneFusionHLA

641 Tumor-related Hotspot Genes














Advantages

  • Panel designed based on GRCh38 and recent patch sequences, covering over 99.9% of the CDS regions in major genetic databases.

  • High accuracy with optimized probe design for repeat regions and high GC content regions.

  • Rigorous quality control with high MAF internal reference QC SNPs.

  • Upgraded TargetSeq One® v2.0 kits and workflow for easier handling and more robust experiment.

  • Compatible with automated workflow to reduce manual operation and human errors.

  • Stable data reproducibility across different NGS platforms, with excellent data performance and outstanding cost-efficiency.



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Performance

Excellent Performance

AIExome® V3 outperforms the major competitors in coverage rate, capture rate and uniformity. It could deliver higher sequence reads utilization rate at lower cost.

Excellent Performance
Stable Data Reproducibility Across NGS platforms

With newly upgraded TargetSeq One® v2.0 reagent kits and workflow, AIExome® V3 is not only simple and robust in workflow, but also excellent and consistent in performance across NGS platforms. The following figures show the performances of 8 Gb randomly selected raw sequencing data.

Stable Data Reproducibility Across NGS platforms

Ordering Info

AIExome® Human Exome Panel V3
Product NamePanel NumberSetCat. No
AIExome® Human Exome Panel V3T600V116 rxnPT1008091
96 rxnPT1008092


Resources

Demo DataSet
  • AIExome® Human Exome Panel V3 (T600V1) demo data
    AIExome® Human Exome Panel V3 (T600V1) demo data
Bed File
  • AIExome® Human Exome Panel V3 (T600V1) bed file
    AIExome® Human Exome Panel V3 (T600V1) bed file