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HBV Panel

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Overview
Cases
Ordering Info
Resources
Articles

Overview

TargetSeq® HBV Panel is designed for HBV typing, HBV mutation detection and HBV-host genomic integration site analysis It is suitable for HBV-related cancer research.

HBV-Panel

Product Specification

Panel Number

T2015XV1

Technical Platform
TargetSeq® Hybridization Capture Sequencing
Coverage Size
17.6 Mb
Reference Database
NCBI/Taxonomy
Reference Genome
5,500 full-length seqeunces of 8 types of HBV
Coverage
HBV genome full length
Storage

-20℃±5℃

Sequence Platform
Illumina / MGI
Recommend Sequencing Read Length
PE150
Recommend Sequencing Data Size and Depth
1 Gb


Advantages

  • Panel designed based on the full length of 5500 HBV genome sequences of 8 subtypes.

  • Compatible with various sample types such as tissue, cells, and plasma.

  • Compatible with both Illumina and MGI sequencing platforms.



Learn more about HBV Panel

Cases

Case Study

The oncogenic effects of preS combination mutations have rarely been studied compared to HBV preS deletions. Using a prospective cohort study including 2114 subjects, the authors found that the preS combination mutations G2950A/G2951A/A2962G/C2964A and C3116T/T31C significantly increased the risk of HCC in patients not receiving antiviral therapy, whereas preS2 deletions significantly increased the risk of HCC in patients receiving antiviral therapy.

HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling HBV preS Mutations Promote Hepatocarcinogenesis by Inducing Endoplasmic Reticulum Stress and Upregulating Inflammatory Signaling
Article
Wenbin Liu 1, Shiliang Cai 1, Rui Pu 1, Zixiong Li 1, Donghong Liu 2, Xinyu Zhou 1, Jianhua Yin 1, Xi Chen 1, Liping Chen 1, Jianfeng Wu 3, Xiaojie Tan 1, Xin Wang 4, Guangwen Cao 1

Ordering Info

HBV Panel
Product NamePanel NumberSetCat. No
TargetSeq® HBV Panel

T2015XV1

16 rxn

PH2001301

96 rxn

PH2001302


Resources

Demo DataSet
  • TargetSeq® HBV Panel (T2015XV1) demo data
    TargetSeq® HBV Panel (T2015XV1) demo data
bed file
  • TargetSeq® HBV Panel (T2015XV1) bed file
    TargetSeq® HBV Panel (T2015XV1) bed file

Articles

Rui Pu; Wenbin Liu; Xinyu Zhou; Xi Chen; Xiaomei Hou; Shiliang Cai; Liping Chen; Jianfeng Wu; Fan Yang; Xiaojie Tan; Jianhua Yin; Xin Wang; Guangwen Cao
Frontiers in Oncology 2022;12:836517 DOI:10.3389/fonc.2022.836517
Fengxue Yu; Xiaolin Zhang; Suzhai Tian; Lianxia Geng; Weili Xu; Ning Ma; Mingbang Wang; Yuan Jia; Xuechen Liu; Junji Ma; Yuan Quan; Chaojun Zhang; Lina Guo; Wenting An; Dianwu Liu
Bioscience Reports 2017;37(6):1-8 DOI:10.1042/BSR20171263
Fengxue Yu; Ning Ma; Xiaolin Zhang; Suzhai Tian; Lianxia Geng; Weili Xu; Mingbang Wang; Yuan Jia; Xuechen Liu; Junji Ma; Yuan Quan; Chaojun Zhang; Lina Guo; Wenting An; Dianwu Liu
Cytokine 2018;103:10-14 DOI:10.1016/j.cyto.2017.12.017
Mingyuan Zhang; Haikun Zhang; Xiaoming Cheng; Xiaomei Wang; Hongqin Xu; Xiuzhu Gao; Ruihong Wu; Dake Zhang; Yuchen Xia; Junqi Niu
Antiviral Research 2022;204:105363 DOI:10.1016/j.antiviral.2022.105363