The all-in-one solution of the gene capture laboratory of iGeneTech was upgraded, and the IGT-AS12 automated liquid workstation was newly launched. The automation upgrade of small and medium-sized NGS gene capture laboratories can effectively reduce manual operation and improve experimental stability.
The new IGT-AS12 automated liquid workstation
01 High-precision transfer
The IGT-AS12 offers a high-precision pipetting robot with a positioning accuracy of ±0.1 mm. With single-channel and 8-channel dual pipettes that can be automatically switched online, it can be adapted to 50 μL and 200 μL pipetting tips at the same time, and 1 μL pipetting CV ≤ 5%, meeting the needs of high-precision NGS experimental procedures with up to 16 reactions in a single experimental throughput.
For higher throughput laboratory testing needs, the IGT-AS12 also offers an upgraded solution for a 24-channel pipette with up to 48 reactions in a single experimental throughput.
02 Flexible collocation
IGT-AS12 provides 12 standard board positions, standard mechanical grippers, and four optional function modules: temperature control module, magnetic separation module, oscillation module, and thermal cycling module. According to the needs of the experiment, it can be flexibly matched with various functional modules, adapters and ice box adapters to fully meet the needs of different NGS gene capture experimental steps such as concentration homogenization, reagent preparation, magnetic bead purification, PCR reaction to library mixing.
The IGT-AS12 design is fully optimized so that the pipette does not occupy the number of plates, and the thermal cycling module only needs to occupy 1 plate position, providing a higher effective plate count.
03 Powerful operating software
The software interface is simple and intuitive, supports drag-and-drop operation, and the operation software provides intelligent process construction solutions, supports customized processes, and fully meets the needs of complex and changeable personalized use.
The operating software is preset with tried-and-tested universal procedures and templates, and provides the standard experimental procedures of the fully validated iGeneTech full range of gene capture kits, which are seamless and easy to use.
04 Comprehensive safety design
The equipment is equipped with ultraviolet sterilization lamps as standard and optional HEPA high-efficiency filters to fully meet the needs of experimental cleanliness. At the same time, it is equipped with specially designed electromagnetic door locks and emergency stop buttons as standard to fully protect the personal safety of equipment and users.
Automated upgrade protocol for targeted sequencing laboratories
IGT-AS12 is designed according to the NGS gene capture experimental process, which is suitable for the automation upgrade of most NGS experimental procedures on the market. It meets the whole process of library construction, meets the experimental needs of the whole process of library construction from concentration homogenization, reagent preparation, magnetic bead purification, PCR reaction to library mixing, and fully meets the automatic upgrade needs of various gene capture experiments such as whole genome construction, whole exome formation library, multiplex amplicon library construction, transcription composition library, hybridization capture and so on.
The IGT-AS12 is available in a variety of configurations to meet the requirements of different laboratory areas, throughputs and degrees of automation. IGT-AS12 also provides an upgrade scheme for 24-channel pipettes to meet the experimental needs of library construction, magnetic bead purification and elution of single-round experiment 48 reactions.
IGT-AS12 can save users up to 90% of manual operation time, completely freeing up manpower. At the same time, the measured data of the TargetSeq® hybridization capture experiment using IGT-AS12 for 8 samples (below) show that IGT-AS12 can comprehensively reduce the variability introduced by manual operation and greatly improve the stability of the experiment.
Whether it is tumor panel detection, MRD monitoring, methylation detection and other tumor applications, or whole exome detection, PGS/PGD and other reproductive genetic testing research, or microbial testing and other NGS application scenarios, IGT-AS12 can help you easily achieve automation upgrades.
Fully adapted, no waiting
Through the NGS probe hybridization and multiplex PCR technology platform with independent core intellectual property rights, iGeneTech has provided more than 1,500 high-standard personalized gene capture products for hundreds of customers in the fields of medical health, agriculture, microbiology, academic research, etc., and provided core raw materials for dozens of NGS IVD products in transit or in the newspaper.
IGT-AS12 has been fully adapted to the standard products and customized products of the widely acclaimed iGeneTech full series of gene capture kits, covering tumor companion diagnosis, genetic disease detection, immunogroup library detection, HLA typing, PGD/PGS detection, genotyping and many other application scenarios, providing different configurations, different throughput, verified iGeneTech full product line kit process, experiments can be carried out on the same day of installation, without waiting.
IGT™ series universal library construction kit
TargetSeq® series hybridization capture kits
BisCap® series methylation hybridization capture kits
MultipSeq® series multiplex amplicon library construction kits
At the same time, IGT-AS12 supports custom configuration and custom process development to meet the complex and changeable needs of different laboratories.
Support customized OEM production
iGeneTech provides a complete all-in-one customized solution for gene capture kits and IGT-AS12 automated liquid workstations with "reagent + equipment" for complete gene capture laboratories to meet the complex and changeable needs of different laboratories, and fully ensure the convenience of using customized kits and the stability and reliability of experimental results.
IGT-AS12 supports customized configuration customization, customized process development and supporting kit development, meets the requirements of various application scenarios and throughput, and fully supports customized OEM production from equipment appearance to operation software.
At the same time, for customized customers, iGeneTech will provide complete medical device registration support for customized gene capture kits and IGT-AS12 equipment, and provide complete maintenance and admission support and other full-cycle services.
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